Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== Intracellular signaling ====== Intracellular [[signaling]] was first elucidated by studies of the action of hormones such as epinephrine, which signals the breakdown of glycogen to glucose in anticipation of muscular activity. In 1958, Earl Sutherland discovered that the action of epinephrine was mediated by an increase in the intracellular concentration of cyclic AMP ([[cAMP]]), leading to the concept that cAMP is a second messenger in hormonal signaling (the first messenger being the hormone itself). intracellular_signaling.txt Last modified: 2024/06/07 02:53by 127.0.0.1