Infection [Neurosurgery Wiki]

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====== Infection ======


Infection is the invasion and multiplication of [[microorganism]]s — such as [[bacteria]], [[virus]]es, [[fungi]], or [[parasite]]s — in the body, which may cause tissue damage and trigger an [[immune response]].

Key Points:
Causative agents: Pathogens (e.g., Streptococcus, influenza virus, Candida, Plasmodium)

Routes of entry: Skin, respiratory tract, gastrointestinal tract, urogenital tract, or bloodstream

Types:

Localized (e.g., skin abscess)

Systemic (e.g., sepsis)

Acute vs. Chronic

Nosocomial (hospital-acquired) vs. community-acquired

Signs/Symptoms: Fever, inflammation, pain, pus, malaise, organ dysfunction (depending on site)

Diagnosis: Cultures, serologies, PCR, imaging

Treatment: Antimicrobials (antibiotics, antivirals, antifungals, antiparasitics), supportive care