Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== HLA-B27 ====== Although the cause of [[ankylosing spondylitis]] is unknown, it is believed to involve a combination of genetic and environmental factors. More than 90% of those affected have a specific [[human leukocyte antigen]] known as the [[HLA-B27]] antigen. The underlying mechanism is believed to be autoimmune or autoinflammatory. ---- but only 2% of people with HLA-B27 develop clinical AS. ---- ---- [[Reiter syndrome]] (after Hans Reiter, a German bacteriologist): a reactive arthritis (usually 1–3 weeks following certain bacterial infections) with involvement of at least one other non-joint area (urethritis, uveitis/conjunctivitis, skin lesions, mucosal ulcerations…). 75% are [[HLA-B27]] positive hla-b27.txt Last modified: 2024/06/07 02:58by 127.0.0.1