HER2-positive brain metastases treatment [Neurosurgery Wiki]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.

====== HER2-positive brain metastases treatment ======


Standard treatment includes local approaches such as [[whole brain radiotherapy]] (WBRT), radiosurgery, and neurosurgery.

Apparently, in selected patients, BM can be controlled with multiple lines of systemic therapy similar to extracranial disease. Further investigation of systemic treatment approaches is therefore warranted
((Bergen ES, Berghoff AS, Rudas M, Preusser M, Bartsch R. Breast cancer brain
metastases responding to lapatinib plus capecitabine as second-line primary
systemic therapy. Anticancer Drugs. 2015 Feb 24. [Epub ahead of print] PubMed
PMID: 25714248.
)).

===== Chemotherapy =====

[[HER2-positive brain metastases chemotherapy]].


===== Stereotactic radiosurgery =====

[[HER2-positive brain metastases stereotactic radiosurgery]].

===== Trastuzumab =====
[[Trastuzumab]]