Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. Biological Pathways in Glioma [[PI3K]]/[[AKT]]/[[mTOR]] [[Pathway]]: Promotes cell growth, proliferation, and survival. Frequently hyperactivated due to PTEN loss or PIK3CA mutations. RAS/MAPK Pathway: Stimulates cell cycle progression and invasion. JAK/STAT3 Pathway: Drives inflammation, immune evasion, and stemness in glioma cells. Notch and Wnt Signaling: Regulate glioma stem cell maintenance and therapy resistance. Metabolic Reprogramming: Warburg effect: Preferential glycolysis even in oxygen-rich conditions. Increased lipid metabolism and glutamine dependence. glioma_biology.txt Last modified: 2025/01/09 11:31by 127.0.0.1