Gelatin Sponge [Neurosurgery Wiki]

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====== Gelatin Sponge ======

{{ ::gelatin_sponge.jpg?200|}}

see [[Spongostan]].

see [[Gelfoam]].

see also [[Hemostat]].
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Expanding the range of medical [[sponge]]s and researching new excipients for their manufacture are a promising area of modern medicine and pharmacy
((Pavliuk B, Chubka M, Hroshovyi T, Stechyshyn I. Characteristics of structured medical hemostatic [[sponge]]s as a medical [[device]]s for stop bleeding and for close the [[wound]]. Pol Merkur Lekarski. 2020 Dec 22;48(288):422-426. PMID: 33387430.)).
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[[Gelatin sponge]] is a non-antigenic [[protein]] that can absorb 45 times its weight in [[blood]], and, when wet, is plastered to the irregularities of the bleeding surface. It enables the repair of torn [[vein]]s, such as the [[superior sagittal sinus]], without compromising the patency of the vessel
((Signorelli F, Montano N. Use and Efficacy of [[Hemostat]]s in [[Neurosurgery]]. Surg Technol Int. 2020 Nov 28;37:414-419. PMID: 32944921.)).
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Many [[ablative]] [[procedure]]s are effective for [[hemifacial spasm]] (HFS) (including sectioning of divisions of the [[facial nerve]]), however, this leaves the patient with some degree of facial paresis. The current procedure of choice for HFS is [[microvascular decompression]] (MVD) wherein the offending vessel is physically moved off of the nerve, and a [[sponge]] (e.g. Ivalon®, polyvinyl formyl alcohol foam) is interposed as a cushion.
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For Chang et al. from the Department of Neurosurgery [[Xinhua Hospital]] in [[hemifacial spasm]] (HFS) patients undergoing [[microvascular decompression]] (MVD) , using [[Teflon]] plus [[gelatin]] [[sponge]] can remarkably reduce the incidence of recurrence, [[facial palsy]], and [[hearing loss]] compared with those using Teflon alone
((Chang B, Tang Y, Wei X, Li S. A New Application of [[Gelatin Sponge]] in the Treatment of [[Hemifacial Spasm]] by [[Microvascular Decompression]]: A Technical Note. [[J Neurol Surg A Cent Eur Neurosurg]]. 2021 May 19. doi: 10.1055/s-0040-1720994. Epub ahead of print. PMID: 34010981.)).
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A study proves that, during the dural closure, placing a thin layer of gelatin sponge in the subdural space is a safe and effective method for preventing meningocerebral adhesions
((Gonzalez-Lopez P, Harput MV, Türe H, Atalay B, Türe U. Efficacy of placing a
thin layer of [[gelatin sponge]] over the [[subdural space]] during [[dural closure]] in
preventing meningo-cerebral adhesion. World Neurosurg. 2015 Jan;83(1):93-101.
doi: 10.1016/j.wneu.2014.02.032. Epub 2014 Feb 19. PubMed PMID: 24560706.
))