Epidermal growth factor receptor [Neurosurgery Wiki]

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====== Epidermal growth factor receptor ======
The [[epidermal growth factor]] [[receptor]] is a member of the [[ErbB]] family of [[receptor]]s, a subfamily of four closely related receptor [[tyrosine kinase]]s: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). 
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EGFR is found on the surface of some normal [[cell]]s and is involved in [[cell growth]]. It may also be found at high levels on some types of [[cancer cell]]s, which causes these cells to grow and divide. Blocking [[EGFR]] may keep cancer cells from growing. Some [[epidermal growth factor receptor tyrosine kinase inhibitor]]s are used to treat cancer. Also called [[EGFR inhibitor]], EGFR tyrosine kinase inhibitor, and epidermal growth factor receptor inhibitor.
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[[Preoperative]] [[assessment]] of [[epidermal growth factor receptor]] ([[EGFR]]) status, response to EGFR-tyrosine kinase inhibitors (TKI), and development of [[T790M]] mutation in [[non-small cell lung cancer]] (NSCLC) patients with [[brain metastases]] (BM) is essential for clinical decision-making, while previous studies were only based on the whole BM
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===== Epidermal growth factor receptor 3 =====

[[Epidermal growth factor receptor 3]].

===== Epidermal growth factor receptor mutation =====

see [[Epidermal growth factor receptor mutation]].

===== Epidermal growth factor receptor in glioblastoma =====

[[Epidermal growth factor receptor in glioblastoma]].