Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. Endothelial inflammation refers to the activation and dysfunction of vascular endothelial cells in response to harmful stimuli (e.g., oxidized lipids, cytokines, infectious agents, or mechanical stress), leading to: Increased expression of adhesion molecules (e.g., VCAM-1, ICAM-1, E-selectin) Leukocyte recruitment and infiltration into the vascular wall Proinflammatory cytokine and chemokine release Loss of endothelial barrier function Pro-thrombotic and pro-oxidative state This process is a key early event in the pathogenesis of atherosclerosis, promoting the transition from a healthy vascular endothelium to a chronically inflamed, dysfunctional surface that facilitates plaque development and progression. endothelial_inflammation.txt Last modified: 2025/06/17 09:40by administrador