Dual antiplatelet therapy complications [Neurosurgery Wiki]

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====== Dual antiplatelet therapy complications ======


Dual [[antiplatelet therapy]] is associated with high early risks of major and [[gastrointestinal bleeding]] that decline after the first month in trial cohorts
((Hilkens NA, Algra A, Kappelle LJ, Bath PM, Csiba L, Rothwell PM, Greving JP;
CAT Collaboration. Early time course of major bleeding on antiplatelet therapy
after TIA or ischemic stroke. Neurology. 2018 Jan 26. pii:
10.1212/WNL.0000000000004997. doi: 10.1212/WNL.0000000000004997. [Epub ahead of
print] PubMed PMID: 29374102.
)).
----
It is known that [[stent-assisted coiling]] (SAC) for ruptured [[wide-neck intracranial aneurysm]]s has a good efficacy; however, there is an increased risk of perioperative hemorrhagic complications due to the
need for [[dual antiplatelet therapy]] (DAPT).
((H. Roh, J. Kim, H. Bae, K. Chong, J.H. Kim, S.I. Suh, T.H. Kwon, W. Yoon,
Comparison of stent-assisted and no-stent coil embolization for safety and effectiveness in the treatment of ruptured intracranial aneurysms, J. Neurosurg.
(2019) 1–7))

[[Ventriculoperitoneal shunt complication after dual antiplatelet therapy]].