Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. Pilocytic astrocytomas range in appearance: Large cystic component with a brightly enhancing [[mural nodule]]: 67% nonenhancing cyst wall: 21% enhancing cyst wall: 46% heterogeneous, mixed solid and multiple cysts and central necrosis: 16% completely solid: 17% Enhancement is almost invariably present (~95%). Up to 20% may demonstrate some calcification. Haemorrhage is a rare complication. ===MRI=== “Classic” MRI finding: posterior fossa cyst with an enhancing mural nodule. The cyst wall sometimes enhances, usually as a thin rim (biopsy negative for neoplasm, enhancement may be reactive ((Beni-Adani L, Gomori M, Spektor S, et al. Cyst wall enhancement in pilocytic astrocytoma: neoplastic or reactive phenomena. Pediatr Neurosurg. 2000; 32:234–239))). Signal characteristics include: T1: iso to hypointense solid component compared to adjacent brain T2: hyperintense solid component compared to adjacent brain {{::cerebellar_pilocytic_astrocytoma_mri.jpg?300|}} [[Apparent diffusion coefficient]] (ADC) values have been shown to assist in differentiating cerebellar pilocytic astrocytomas and [[medulloblastoma]]s. Previous studies have applied only ADC measurements and calculated the mean/median values. The 25th percentile for mean (MD) yields the best results for the presurgical differentiation between pediatric cerebellar pilocytic astrocytomas and medulloblastomas. The analysis of other [[DTI]] metrics does not provide additional diagnostic value ((Wagner MW, Narayan AK, Bosemani T, Huisman TA, Poretti A. Histogram Analysis of Diffusion Tensor Imaging Parameters in Pediatric Cerebellar Tumors. J Neuroimaging. 2015 Sep 2. doi: 10.1111/jon.12292. [Epub ahead of print] PubMed PMID: 26331360. )). cerebellar_pilocytic_astrocytoma_diagnosis.txt Last modified: 2024/06/07 02:57by 127.0.0.1