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--- unicoronal_craniosynostosis [2025/07/16 22:11] – [Treatment of Unicoronal Craniosynostosis] administrador
+++ unicoronal_craniosynostosis [2025/07/16 22:12] (current) – [Unicoronal Craniosynostosis: Classification] administrador
@@ Line 12: / Line 12: @@
 Deraje V, Gopal S, Mendonca DA, Gujjalanavar RS. Endoscope-Assisted "Extended" Suturectomy for Unicoronal Craniosynostosis: A Technical Note. Plast Reconstr Surg. 2021 Oct 26. doi: 10.1097/PRS.0000000000008531. Epub ahead of print. PMID: 34705741.
+===== Unicoronal Craniosynostosis: Epidemiology =====
+Unicoronal craniosynostosis is a relatively uncommon but well-recognized form of isolated craniosynostosis.
+==== 📊 General Epidemiology ====
+  * Represents **20–25%** of all **nonsyndromic craniosynostosis** cases.
+  * More common than bicoronal but less frequent than sagittal synostosis.
+  * Estimated incidence of **1 in 10,000 live births**.
+==== ⚖️ Sex Distribution ====
+  * Slight female predominance:
+    * Female:Male ratio ≈ **3:2**
+==== 🧬 Syndromic vs Nonsyndromic Forms ====
+  * **~85–90%** are **nonsyndromic** (isolated)
+  * **~10–15%** are **syndromic**, commonly associated with:
+    * **Muenke syndrome (FGFR3 mutation)**
+    * **Saethre-Chotzen syndrome (TWIST1 mutation)**
+==== 🕒 Age at Diagnosis ====
+  * Typically diagnosed between **3 and 6 months of age**
+  * Severe cases may be noticed in the **first weeks of life**
+==== 🌍 Geographic and Ethnic Factors ====
+  * No significant racial or geographic predilection reported.
+  * Most studies are based on European and North American populations.
+==== 📌 Notes ====
+  * Early diagnosis is increasing due to improved awareness and imaging availability.
+  * Positional plagiocephaly should always be ruled out via clinical exam and 3D imaging.
 ===== Unicoronal Craniosynostosis: Classification =====