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--- lung_adenocarcinoma [2025/07/18 06:26] – administrador
+++ lung_adenocarcinoma [2025/07/18 06:34] (current) – administrador
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 [[EGFR-Mutant Non-Small-Cell Lung Cancer]].
-====== Surgical Outcomes of Video-Assisted Thoracic Surgery Combined With Computed Tomography-Guided Microwave Ablation for Lung Cancer Presenting as Multiple Ground-Glass Opacities: A 5-Year Retrospective Cohort Study ======
-**Type of Study:**
-Retrospective cohort study (5 years)
-**Authors:**
-Bin Huang et al.
-**Affiliations:**
-Shanghai Children's Medical Center, Shanghai;
-Nanjing Drum Tower Hospital, Nanjing;
-Jiangsu Cancer Hospital, Nanjing;
-Guangdong Provincial People's Hospital, Guangzhou;
-Radboud University Medical Center, Nijmegen;
-Xinhua Hospital, Shanghai
-**Journal:**
-Thoracic Cancer
-**Purpose:**
-To evaluate the feasibility, safety, and long-term outcomes of combining video-assisted thoracic surgery (VATS) with CT-guided microwave ablation (MWA) in treating synchronous multiple primary lung cancers (sMPLC) presenting as multiple ground-glass opacities (mGGOs).
-**Conclusions:**
-The combined VATS and CT-guided MWA approach achieved a 100% technical success rate and demonstrated strong 3-year and 5-year survival metrics, with no observed local tumor progression or recurrence.
-**Critical Review:**
-This single-institution retrospective study offers a bold and innovative combination of VATS and MWA to address the increasingly common issue of mGGOs in early-stage lung adenocarcinoma. While the technical success and survival rates reported are impressive, the lack of a control group, small sample size (n=47), and potential for significant selection bias limit the generalizability of the findings. No details are provided on standardized criteria for nodule selection, ablation parameters, or postoperative surveillance protocols. The “needle and scalpel” rhetoric, though catchy, risks overselling the concept without robust comparative evidence.
-**Final Verdict:**
-A creative surgical strategy with potential, but its evidence base remains preliminary.
-**Takeaway for the Practicing Neurosurgeon:**
-Although not directly applicable to neurosurgical practice, the procedural model exemplifies a multidisciplinary, [[hybrid technique]] that may inspire similar integrated approaches in neuro-oncology.
-**Bottom Line:**
-Promising hybrid therapy for sMPLC with mGGOs, but confirmation in controlled, multicenter trials is essential.
-**Rating:** 5.5 / 10
-**Title:**
-Surgical Outcomes of Video-Assisted Thoracic Surgery Combined With Computed Tomography-Guided Microwave Ablation for Lung Cancer Presenting as Multiple Ground-Glass Opacities: A 5-Year Retrospective Cohort Study
-**Citation:**
-Bin Huang et al. "Surgical Outcomes of Video-Assisted Thoracic Surgery Combined With Computed Tomography-Guided Microwave Ablation for Lung Cancer Presenting as Multiple Ground-Glass Opacities: A 5-Year Retrospective Cohort Study." *Thorac Cancer*. 2025 Jul;16(14):e70120. doi: 10.1111/1759-7714.70120.
-**Publication Date:**
-July 2025
-**Corresponding Author Email:**
-Not provided in the abstract. Must consult full text or publisher’s site.
-**Categories:**
-Lung Cancer, Thoracic Surgery, Hybrid Procedures, Oncology
-**Tags:**
-VATS, microwave ablation, ground-glass opacities, mGGOs, sMPLC, lung cancer, thoracic oncology, retrospective study, surgical innovation