experimental_animal_study

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experimental_animal_study [2024/12/20 07:06] – created - external edit 127.0.0.1experimental_animal_study [2025/07/06 08:00] (current) – administrador
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 An [[experimental]] [[animal study]] is a type of [[scientific research]] that involves the use of [[animal model]]s to investigate specific biological, medical, or surgical [[question]]s under controlled conditions. The purpose is to simulate human conditions, study disease mechanisms, or evaluate the [[safety]] and [[efficacy]] of new treatments, devices, or interventions before they are tested in humans. An [[experimental]] [[animal study]] is a type of [[scientific research]] that involves the use of [[animal model]]s to investigate specific biological, medical, or surgical [[question]]s under controlled conditions. The purpose is to simulate human conditions, study disease mechanisms, or evaluate the [[safety]] and [[efficacy]] of new treatments, devices, or interventions before they are tested in humans.
 +
 +====== Preclinical vs Experimental Animal Study ======
 +
 +While closely related, **preclinical animal studies** and **experimental animal studies** are not exactly the same. Below is a structured comparison:
 +
 +^ Feature                          ^ Preclinical Animal Study                             ^ Experimental Animal Study                             ^
 +| **Definition**                   | Subset of animal research aimed at clinical translation | Broad category of studies involving animals           |
 +| **Primary Purpose**              | To evaluate safety, toxicity, pharmacokinetics, and preliminary efficacy before human trials | To explore biological mechanisms, disease models, or test hypotheses |
 +| **Regulatory Context**           | Required for regulatory submission (e.g., [[FDA]] IND) | Not necessarily linked to regulatory processes        |
 +| **Goal**                         | Support first-in-human trials                         | Generate scientific knowledge, may or may not be translational |
 +| **Typical Outputs**              | Data for dose selection, risk assessment, trial design | Mechanistic insights, disease modeling, biomarker discovery |
 +| **Examples**                     | Testing new drug in mice before human trial           | Studying gene expression changes in Alzheimer’s mice  |
 +| **Field**                        | Translational / applied research                      | Basic or applied research                             |
 +| **Scope**                        | Narrower: focused on clinical applicability           | Broader: includes all types of animal experimentation |
 +
 +----
 +
 +**Summary**:  
 +  * All **preclinical animal studies** are **experimental**,  
 +  * But not all **experimental animal studies** are **preclinical**.
 +
 +----
 +
 +**Tags**: preclinical, experimental, animal studies, translational research, basic science, IND
 +
  
 ===== Key Features ===== ===== Key Features =====
  • experimental_animal_study.txt
  • Last modified: 2025/07/06 08:00
  • by administrador