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| amyloid_plaque [2025/07/06 12:44] – created administrador | amyloid_plaque [2025/07/06 12:44] (current) – administrador |
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| **Definition**: | **Definition**: |
| Amyloid plaques are **extracellular deposits** primarily composed of **aggregated amyloid-beta (Aβ) peptides**, especially **Aβ₁–₄₂**, found in the brain parenchyma. They are one of the two pathological hallmarks of **Alzheimer’s disease (AD)**, along with **neurofibrillary tangles** composed of hyperphosphorylated tau protein. | [[Amyloid]] [[plaque]]s are **extracellular deposits** primarily composed of **aggregated amyloid-beta (Aβ) peptides**, especially **Aβ₁–₄₂**, found in the brain parenchyma. They are one of the two pathological hallmarks of **Alzheimer’s disease (AD)**, along with **neurofibrillary tangles** composed of hyperphosphorylated tau protein. |
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| ===== 🧬 Composition ===== | ===== 🧬 Composition ===== |